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The 13th Workshop on the CCN Family of Genes celebrated the 25th anniversary of the founding of the International CCN Society (ICCNS). For the first time since its inception, the workshop was held in Nice, France, from 13 to 17 December 2025, in conjunction with the inaugural ARBIOCOM (ARBC) World Conference on Biosignaling and Communication. A report of this conference is presently in press in the Journal of Cell Communication and Signaling (Wiley). A report on the conference is currently in press in the Journal of Cell Communication and Signaling (Wiley).